CPT Code: 82164
Order Code: 683
ABN Requirement: No
Alternative Name(s): Angiotensin-1-Converting Enzyme, ACE
Specimen:
Preferred: Serum
Alternate: Lithium Heparin Plasma
Volume: 1.0 mL
Minimum Volume: 0.5 mL
Container:
Preferred: Serum Separator Tube (SST; Gel Barrier) Plasma collected in: Sodium Heparin (green-top) tube Lithium Heparin (green-top) tube
Alternate: Green Top (Lithium Heparin) Tube
Collection:
Serum (preferred):
- Collect and label sample according to standard protocols.
- Gently invert tube 5 times immediately after draw. Do not shake.
- Allow blood to clot 30 minutes.
- Centrifuge for 10 minutes.
Lithium Heparin Plasma (alternative):
- Collect and label sample according to standard protocols.
- Gently invert tube 10 times immediately after draw. Do not shake.
- Centrifuge for 10 minutes.
- Aliquot plasma into transport tube labeled as “Lithium Heparin Plasma” and cap tightly.
Discard original tube.
Collection Instructions: Centrifuge specimen within 1 hour of collection.
Transport: Store specimen at 2°C to 8°C after collection and ship the same day per packaging instructions included with the provided shipping box.
Stability:
Ambient (15-25°C): 7 days
Refrigerated (2-8°C): 7 days
Frozen (-20°C): 60 days
Causes for Rejection: Gross hemolysis; Grossly lipemic
Methodology: Spectrophotometry (SP)
Turn Around Time: 2 to 4 days
Reference Range:
| Age | Reference Range (U/L) |
| 6 Months-17 Years | 13-100 U/L |
| Adult | 9-67 U/L |
Clinical Significance: This test is useful in evaluating patients presenting with sarcoidosis, Gaucher’s disease, and lymphangiomyomatosis in that the enzyme is increased in these clinical settings.
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.